Novel Mechanisms for the Antifibrotic Action of Nintedanib. [electronic resource]
Producer: 20160502Description: 51-9 p. digitalISSN:- 1535-4989
- Apoptosis Regulatory Proteins -- genetics
- Autophagy-Related Protein 7
- Beclin-1
- Cells, Cultured
- Collagen Type I -- genetics
- Collagen Type I, alpha 1 Chain
- Dose-Response Relationship, Drug
- Fibronectins -- genetics
- Humans
- Idiopathic Pulmonary Fibrosis -- genetics
- Indoles -- pharmacology
- Lung -- drug effects
- Membrane Proteins -- genetics
- Phosphorylation
- Protein Serine-Threonine Kinases -- metabolism
- RNA Interference
- RNA, Messenger -- metabolism
- Receptor, Transforming Growth Factor-beta Type II
- Receptors, Transforming Growth Factor beta -- metabolism
- Signal Transduction -- drug effects
- Smad3 Protein -- metabolism
- Time Factors
- Transfection
- Transforming Growth Factor beta1 -- metabolism
- Ubiquitin-Activating Enzymes -- genetics
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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