A novel approach for quantitation of nonderivatized sialic acid in protein therapeutics using hydrophilic interaction chromatographic separation and nano quantity analyte detection. [electronic resource]
Producer: 20150908Description: 15-24 p. digitalISSN:- 1520-6017
- Aerosols
- Algorithms
- Analytic Sample Preparation Methods
- Chemistry, Pharmaceutical -- methods
- Chromatography, High Pressure Liquid
- Drug Contamination -- prevention & control
- Glycoproteins -- chemistry
- Hydrophobic and Hydrophilic Interactions
- Limit of Detection
- Models, Molecular
- N-Acetylneuraminic Acid -- analysis
- Nanotechnology
- Nephelometry and Turbidimetry
- Particle Size
- Recombinant Proteins -- chemistry
- Refractometry
- Reproducibility of Results
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Publication Type: Comparative Study; Evaluation Study; Journal Article
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