Celastrol protects ischaemic myocardium through a heat shock response with up-regulation of haeme oxygenase-1. [electronic resource]
Producer: 20150814Description: 5265-79 p. digitalISSN:- 1476-5381
- Animals
- Cardiotonic Agents -- pharmacology
- Cell Line
- Cell Survival -- drug effects
- DNA-Binding Proteins -- metabolism
- Female
- HSP70 Heat-Shock Proteins -- metabolism
- Heat Shock Transcription Factors
- Heat-Shock Response -- drug effects
- Heme Oxygenase (Decyclizing) -- biosynthesis
- Hypoxia -- metabolism
- MAP Kinase Signaling System -- drug effects
- Myocardial Ischemia -- drug therapy
- Myocardium -- pathology
- Oncogene Protein v-akt -- metabolism
- Pentacyclic Triterpenes
- Phosphatidylinositol 3-Kinases -- metabolism
- Rats, Sprague-Dawley
- Reactive Oxygen Species -- metabolism
- Transcription Factors -- metabolism
- Triterpenes -- pharmacology
- Up-Regulation
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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