The HIF-2alpha dependent induction of PAP and adenosine synthesis regulates glioblastoma stem cell function through the A2B adenosine receptor. [electronic resource]
Producer: 20141121Description: 8-16 p. digitalISSN:- 1878-5875
- Acid Phosphatase
- Adenosine -- biosynthesis
- Adenosine A2 Receptor Antagonists -- pharmacology
- Animals
- Basic Helix-Loop-Helix Transcription Factors -- genetics
- Blotting, Western
- Cell Hypoxia
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Cells, Cultured
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Female
- Glioblastoma -- genetics
- Humans
- Male
- Neoplastic Stem Cells -- drug effects
- Phosphorylation
- Protein Tyrosine Phosphatases -- genetics
- Proto-Oncogene Proteins c-akt -- metabolism
- RNA Interference
- Rats
- Rats, Nude
- Receptor, Adenosine A2B -- genetics
- Tumor Cells, Cultured
- Xanthines -- pharmacology
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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