Induced resistance to ofatumumab-mediated cell clearance mechanisms, including complement-dependent cytotoxicity, in chronic lymphocytic leukemia. [electronic resource]
Producer: 20140414Description: 1620-9 p. digitalISSN:- 1550-6606
- Adult
- Aged
- Aged, 80 and over
- Alemtuzumab
- Antibodies, Monoclonal -- blood
- Antibodies, Monoclonal, Humanized -- therapeutic use
- Antigens, CD -- biosynthesis
- Antigens, CD20 -- biosynthesis
- Antigens, Neoplasm -- biosynthesis
- Antineoplastic Agents -- therapeutic use
- Antineoplastic Combined Chemotherapy Protocols -- therapeutic use
- B-Lymphocytes -- cytology
- CD52 Antigen
- Complement System Proteins -- metabolism
- Cyclophosphamide -- therapeutic use
- Cytotoxicity, Immunologic -- immunology
- Drug Resistance, Neoplasm
- Female
- Glycoproteins -- biosynthesis
- Humans
- Leukemia, Lymphocytic, Chronic, B-Cell -- drug therapy
- Lymphocyte Count
- Male
- Middle Aged
- Pentostatin -- therapeutic use
- Treatment Outcome
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Publication Type: Clinical Trial, Phase II; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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