A novel sirtuin 2 (SIRT2) inhibitor with p53-dependent pro-apoptotic activity in non-small cell lung cancer. [electronic resource]
Producer: 20140422Description: 5208-16 p. digitalISSN:- 1083-351X
- Acetylation -- drug effects
- Apoptosis -- drug effects
- Carcinoma, Non-Small-Cell Lung -- drug therapy
- Drug Screening Assays, Antitumor
- Etoposide -- pharmacology
- Gene Expression Regulation, Neoplastic -- drug effects
- Histone Deacetylase Inhibitors -- chemistry
- Humans
- Inhibitory Concentration 50
- Lung Neoplasms -- drug therapy
- Neoplasm Proteins -- genetics
- Sirtuin 2 -- antagonists & inhibitors
- Tumor Suppressor Protein p53 -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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