α-santalol inhibits the angiogenesis and growth of human prostate tumor growth by targeting vascular endothelial growth factor receptor 2-mediated AKT/mTOR/P70S6K signaling pathway. [electronic resource]
Producer: 20140717Description: 147 p. digitalISSN:- 1476-4598
- Angiogenesis Inhibitors -- pharmacology
- Animals
- Apoptosis -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Gene Expression Regulation, Neoplastic
- Human Umbilical Vein Endothelial Cells
- Humans
- Male
- Mice
- Mice, Nude
- Models, Molecular
- Molecular Docking Simulation
- Molecular Targeted Therapy
- Neovascularization, Pathologic -- drug therapy
- Polycyclic Sesquiterpenes
- Prostate -- metabolism
- Prostatic Neoplasms -- drug therapy
- Proto-Oncogene Proteins c-akt -- genetics
- Rats
- Sesquiterpenes -- pharmacology
- Signal Transduction -- drug effects
- Vascular Endothelial Growth Factor Receptor-2 -- antagonists & inhibitors
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Retracted Publication
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