Statin therapy reduces the mycobacterium tuberculosis burden in human macrophages and in mice by enhancing autophagy and phagosome maturation. [electronic resource]
Producer: 20140603Description: 754-63 p. digitalISSN:- 1537-6613
- Animals
- Autophagy -- drug effects
- Cholesterol -- metabolism
- Drug Resistance, Bacterial -- physiology
- Humans
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Leukocytes, Mononuclear -- drug effects
- Macrophages -- drug effects
- Mice
- Mice, Inbred C57BL
- Mycobacterium tuberculosis -- drug effects
- Phagosomes -- drug effects
- Tuberculosis -- drug therapy
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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