Peripheral reduction of FGFR4 with antisense oligonucleotides increases metabolic rate and lowers adiposity in diet-induced obese mice. [electronic resource]
Producer: 20140218Description: e66923 p. digitalISSN:- 1932-6203
- Adiposity -- drug effects
- Animals
- Basal Metabolism -- drug effects
- Bile Acids and Salts -- metabolism
- Body Weight -- drug effects
- Caloric Restriction
- Diet
- Drug Therapy, Combination
- Fatty Acids -- metabolism
- Fatty Liver -- blood
- Feeding Behavior -- drug effects
- Fibroblast Growth Factors -- blood
- Gene Expression Regulation -- drug effects
- Hepatocytes -- drug effects
- Insulin -- pharmacology
- Liver -- drug effects
- Mice
- Mice, Inbred C57BL
- Mice, Obese
- Obesity -- blood
- Oligonucleotides, Antisense -- pharmacology
- Oxidation-Reduction -- drug effects
- Piperidines -- pharmacology
- Pyrazoles -- pharmacology
- Receptor, Cannabinoid, CB1 -- antagonists & inhibitors
- Receptor, Fibroblast Growth Factor, Type 4 -- genetics
- Rimonabant
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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