Resveratrol mitigates isoflurane-induced neuroapoptosis by inhibiting the activation of the Akt-regulated mitochondrial apoptotic signaling pathway. [electronic resource]
Producer: 20140327Description: 819-26 p. digitalISSN:- 1791-244X
- Anesthetics, Inhalation -- adverse effects
- Animals
- Apoptosis -- drug effects
- Caspase 3 -- genetics
- Caspase 8 -- genetics
- Caspase 9 -- genetics
- Comet Assay
- DNA Damage -- drug effects
- In Situ Nick-End Labeling
- Isoflurane -- adverse effects
- Mice
- Mice, Inbred BALB C
- Mitochondria -- drug effects
- Mitochondrial Membrane Transport Proteins -- metabolism
- Mitochondrial Permeability Transition Pore
- Neurons -- cytology
- Neuroprotective Agents -- pharmacology
- Oxidative Stress -- drug effects
- Proto-Oncogene Proteins c-akt -- genetics
- Reactive Oxygen Species -- metabolism
- Resveratrol
- Signal Transduction
- Stilbenes -- pharmacology
- Superoxide Dismutase -- genetics
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Publication Type: Journal Article
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