BIRB796, the inhibitor of p38 mitogen-activated protein kinase, enhances the efficacy of chemotherapeutic agents in ABCB1 overexpression cells. [electronic resource]
Producer: 20130724Description: e54181 p. digitalISSN:- 1932-6203
- ATP Binding Cassette Transporter, Subfamily B
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- genetics
- Animals
- Antineoplastic Agents, Phytogenic -- pharmacology
- Blotting, Western
- Cell Line, Tumor
- Cell Survival -- drug effects
- Drug Resistance, Multiple -- drug effects
- Drug Resistance, Neoplasm -- drug effects
- Drug Synergism
- Gene Expression Regulation, Neoplastic
- HEK293 Cells
- HL-60 Cells
- Humans
- MCF-7 Cells
- Mice
- Mice, Inbred BALB C
- Mice, Nude
- Naphthalenes -- pharmacology
- Neoplasms -- drug therapy
- Paclitaxel -- pharmacology
- Protein Kinase Inhibitors -- pharmacology
- Pyrazoles -- pharmacology
- RNA Interference
- Reverse Transcriptase Polymerase Chain Reaction
- Xenograft Model Antitumor Assays
- p38 Mitogen-Activated Protein Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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