Loss and gain of Drosophila TDP-43 impair synaptic efficacy and motor control leading to age-related neurodegeneration by loss-of-function phenotypes. [electronic resource]
Producer: 20130903Description: 1539-57 p. digitalISSN:- 1460-2083
- Aging
- Amyotrophic Lateral Sclerosis -- genetics
- Animals
- Animals, Genetically Modified
- DNA-Binding Proteins -- genetics
- Disease Models, Animal
- Drosophila melanogaster -- genetics
- Frontotemporal Lobar Degeneration -- genetics
- Larva
- Nerve Degeneration -- genetics
- Neuromuscular Junction -- metabolism
- Neurons -- metabolism
- Phenotype
- Synaptic Transmission -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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