β1-Adrenoceptor autoantibodies from DCM patients enhance the proliferation of T lymphocytes through the β1-AR/cAMP/PKA and p38 MAPK pathways. [electronic resource]
Producer: 20130624Description: e52911 p. digitalISSN:- 1932-6203
- Adrenergic beta-1 Receptor Antagonists -- pharmacology
- Adrenergic beta-Agonists -- pharmacology
- Aged
- Animals
- Autoantibodies -- blood
- Cardiomyopathy, Dilated -- immunology
- Cell Proliferation -- drug effects
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- Female
- Humans
- Imidazoles -- pharmacology
- Interferon-gamma -- metabolism
- Isoproterenol -- pharmacology
- Isoquinolines -- pharmacology
- Male
- Metoprolol -- pharmacology
- Middle Aged
- Phosphorylation -- drug effects
- Protein Kinase Inhibitors -- pharmacology
- Pyridines -- pharmacology
- Rats
- Rats, Sprague-Dawley
- Receptors, Adrenergic, beta-1 -- immunology
- Signal Transduction -- drug effects
- Sulfonamides -- pharmacology
- T-Lymphocytes -- drug effects
- p38 Mitogen-Activated Protein Kinases -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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