Monotropein isolated from the roots of Morinda officinalis ameliorates proinflammatory mediators in RAW 264.7 macrophages and dextran sulfate sodium (DSS)-induced colitis via NF-κB inactivation. [electronic resource]
Producer: 20130826Description: 263-71 p. digitalISSN:- 1873-6351
- Animals
- Anti-Inflammatory Agents -- pharmacology
- Cell Line, Tumor
- Colitis -- chemically induced
- Cyclooxygenase 2 -- genetics
- Dextran Sulfate -- adverse effects
- I-kappa B Proteins -- genetics
- Inflammation Mediators -- antagonists & inhibitors
- Interleukin-1beta -- genetics
- Iridoids -- pharmacology
- Lipopolysaccharides -- adverse effects
- Macrophages -- drug effects
- Mice
- Morinda -- chemistry
- NF-KappaB Inhibitor alpha
- NF-kappa B -- antagonists & inhibitors
- Nitric Oxide Synthase Type II -- genetics
- Peroxidase -- metabolism
- Phosphorylation
- Plant Roots -- chemistry
- RNA, Messenger -- genetics
- Tumor Necrosis Factor-alpha -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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