NCKX5, a natural regulator of human skin colour variation, regulates the expression of key pigment genes MC1R and alpha-MSH and alters cholesterol homeostasis in normal human melanocytes. [electronic resource]
Producer: 20130314Description: 95-107 p. digitalISSN:- 0065-2598
- Amino Acid Substitution
- Antiporters -- genetics
- Cholesterol -- genetics
- Gene Expression Profiling
- Gene Expression Regulation -- physiology
- Homeostasis -- physiology
- Humans
- Melanocytes -- metabolism
- Mutation, Missense
- Polymorphism, Single Nucleotide
- Protein Structure, Tertiary
- Receptor, Melanocortin, Type 1 -- biosynthesis
- Skin -- metabolism
- Skin Pigmentation -- physiology
- alpha-MSH -- biosynthesis
- trans-Golgi Network -- genetics
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Publication Type: Journal Article; Review
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