NCKX5, a natural regulator of human skin colour variation, regulates the expression of key pigment genes MC1R and alpha-MSH and alters cholesterol homeostasis in normal human melanocytes.
Wilson, Stephen
NCKX5, a natural regulator of human skin colour variation, regulates the expression of key pigment genes MC1R and alpha-MSH and alters cholesterol homeostasis in normal human melanocytes. [electronic resource] - Advances in experimental medicine and biology 2013 - 95-107 p. digital
Publication Type: Journal Article; Review
0065-2598
10.1007/978-1-4614-4756-6_9 doi
Amino Acid Substitution
Antiporters--genetics
Cholesterol--genetics
Gene Expression Profiling
Gene Expression Regulation--physiology
Homeostasis--physiology
Humans
Melanocytes--metabolism
Mutation, Missense
Polymorphism, Single Nucleotide
Protein Structure, Tertiary
Receptor, Melanocortin, Type 1--biosynthesis
Skin--metabolism
Skin Pigmentation--physiology
alpha-MSH--biosynthesis
trans-Golgi Network--genetics
NCKX5, a natural regulator of human skin colour variation, regulates the expression of key pigment genes MC1R and alpha-MSH and alters cholesterol homeostasis in normal human melanocytes. [electronic resource] - Advances in experimental medicine and biology 2013 - 95-107 p. digital
Publication Type: Journal Article; Review
0065-2598
10.1007/978-1-4614-4756-6_9 doi
Amino Acid Substitution
Antiporters--genetics
Cholesterol--genetics
Gene Expression Profiling
Gene Expression Regulation--physiology
Homeostasis--physiology
Humans
Melanocytes--metabolism
Mutation, Missense
Polymorphism, Single Nucleotide
Protein Structure, Tertiary
Receptor, Melanocortin, Type 1--biosynthesis
Skin--metabolism
Skin Pigmentation--physiology
alpha-MSH--biosynthesis
trans-Golgi Network--genetics