Transcriptional regulation of specific protein 1 (SP1) by hypoxia-inducible factor 1 alpha (HIF-1α) leads to PRNP expression and neuroprotection from toxic prion peptide. [electronic resource]
Producer: 20130402Description: 93-8 p. digitalISSN:- 1090-2104
- Apoptosis -- drug effects
- Cell Hypoxia
- Cell Line, Tumor
- Gene Expression Regulation
- Humans
- Hypoxia-Inducible Factor 1, alpha Subunit -- genetics
- Neurons -- drug effects
- Peptide Fragments -- pharmacology
- Prion Diseases -- genetics
- Prion Proteins
- Prions -- genetics
- Signal Transduction
- Sp1 Transcription Factor -- genetics
- Transcription, Genetic
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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