Transcriptional regulation of specific protein 1 (SP1) by hypoxia-inducible factor 1 alpha (HIF-1α) leads to PRNP expression and neuroprotection from toxic prion peptide.

Jeong, Jae-Kyo

Transcriptional regulation of specific protein 1 (SP1) by hypoxia-inducible factor 1 alpha (HIF-1α) leads to PRNP expression and neuroprotection from toxic prion peptide. [electronic resource] - Biochemical and biophysical research communications Dec 2012 - 93-8 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1090-2104

10.1016/j.bbrc.2012.10.086 doi


Apoptosis--drug effects
Cell Hypoxia
Cell Line, Tumor
Gene Expression Regulation
Humans
Hypoxia-Inducible Factor 1, alpha Subunit--genetics
Neurons--drug effects
Peptide Fragments--pharmacology
Prion Diseases--genetics
Prion Proteins
Prions--genetics
Signal Transduction
Sp1 Transcription Factor--genetics
Transcription, Genetic