Alzheimer's β-secretase (BACE1) regulates the cAMP/PKA/CREB pathway independently of β-amyloid. [electronic resource]
Producer: 20121102Description: 11390-5 p. digitalISSN:- 1529-2401
- Amyloid Precursor Protein Secretases -- genetics
- Amyloid beta-Peptides -- metabolism
- Amyloid beta-Protein Precursor -- deficiency
- Animals
- Aspartic Acid Endopeptidases -- genetics
- Brain -- cytology
- CREB-Binding Protein -- metabolism
- Cells, Cultured
- Colforsin -- pharmacology
- Cyclic AMP -- metabolism
- Cyclic AMP-Dependent Protein Kinases -- metabolism
- Disks Large Homolog 4 Protein
- Embryo, Mammalian
- Gene Expression Regulation -- drug effects
- Green Fluorescent Proteins -- genetics
- Guanylate Kinases -- metabolism
- MARVEL Domain-Containing Proteins
- Membrane Proteins -- deficiency
- Mice
- Mice, Inbred C57BL
- Mice, Transgenic
- Mutation -- genetics
- Neuroblastoma -- pathology
- Phosphorylation -- drug effects
- Proteolipids
- Signal Transduction -- physiology
- Synaptophysin -- metabolism
- Transfection
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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