GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis. [electronic resource]
Producer: 20120618Description: 837-48 p. digitalISSN:- 1878-1551
- Animals
- Biomarkers -- metabolism
- Blotting, Western
- Body Patterning
- Bone Morphogenetic Proteins -- genetics
- Cell Proliferation
- Chondrogenesis -- physiology
- Flow Cytometry
- Fluorescent Antibody Technique
- Gene Expression Profiling
- Gene Expression Regulation, Developmental
- Hand Deformities -- etiology
- Kruppel-Like Transcription Factors -- physiology
- Limb Buds -- cytology
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Nerve Tissue Proteins -- physiology
- Oligonucleotide Array Sequence Analysis
- Polydactyly -- pathology
- RNA, Messenger -- genetics
- Real-Time Polymerase Chain Reaction
- S Phase -- physiology
- Stem Cells -- cytology
- Zinc Finger Protein Gli3
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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