GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis.
Lopez-Rios, Javier
GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis. [electronic resource] - Developmental cell Apr 2012 - 837-48 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1878-1551
10.1016/j.devcel.2012.01.006 doi
Animals
Biomarkers--metabolism
Blotting, Western
Body Patterning
Bone Morphogenetic Proteins--genetics
Cell Proliferation
Chondrogenesis--physiology
Flow Cytometry
Fluorescent Antibody Technique
Gene Expression Profiling
Gene Expression Regulation, Developmental
Hand Deformities--etiology
Kruppel-Like Transcription Factors--physiology
Limb Buds--cytology
Mice
Mice, Inbred C57BL
Mice, Knockout
Nerve Tissue Proteins--physiology
Oligonucleotide Array Sequence Analysis
Polydactyly--pathology
RNA, Messenger--genetics
Real-Time Polymerase Chain Reaction
S Phase--physiology
Stem Cells--cytology
Zinc Finger Protein Gli3
GLI3 constrains digit number by controlling both progenitor proliferation and BMP-dependent exit to chondrogenesis. [electronic resource] - Developmental cell Apr 2012 - 837-48 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1878-1551
10.1016/j.devcel.2012.01.006 doi
Animals
Biomarkers--metabolism
Blotting, Western
Body Patterning
Bone Morphogenetic Proteins--genetics
Cell Proliferation
Chondrogenesis--physiology
Flow Cytometry
Fluorescent Antibody Technique
Gene Expression Profiling
Gene Expression Regulation, Developmental
Hand Deformities--etiology
Kruppel-Like Transcription Factors--physiology
Limb Buds--cytology
Mice
Mice, Inbred C57BL
Mice, Knockout
Nerve Tissue Proteins--physiology
Oligonucleotide Array Sequence Analysis
Polydactyly--pathology
RNA, Messenger--genetics
Real-Time Polymerase Chain Reaction
S Phase--physiology
Stem Cells--cytology
Zinc Finger Protein Gli3