Detection of allosteric kinase inhibitors by displacement of active site probes. [electronic resource]
Producer: 20120920Description: 813-21 p. digitalISSN:- 1552-454X
- Adenosine Triphosphate -- metabolism
- Allosteric Regulation -- drug effects
- Binding, Competitive
- Catalytic Domain -- drug effects
- Drug Evaluation, Preclinical -- methods
- Fluorescence Resonance Energy Transfer
- Fusion Proteins, bcr-abl -- antagonists & inhibitors
- Humans
- Inhibitory Concentration 50
- MAP Kinase Kinase 1 -- antagonists & inhibitors
- Protein Binding
- Protein Kinase Inhibitors -- chemistry
- Protein-Tyrosine Kinases -- antagonists & inhibitors
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Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't
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