Protective and therapeutic efficacy of Mycobacterium smegmatis expressing HBHA-hIL12 fusion protein against Mycobacterium tuberculosis in mice. [electronic resource]
Producer: 20120629Description: e31908 p. digitalISSN:- 1932-6203
- Animals
- Antigens, Bacterial -- immunology
- Bacterial Proteins -- pharmacology
- Blotting, Western
- Cloning, Molecular
- Enzyme-Linked Immunospot Assay
- Fluorescent Antibody Technique
- Humans
- Immunization
- Interferon-gamma -- immunology
- Interleukin-12 -- pharmacology
- Lung -- drug effects
- Membrane Proteins -- pharmacology
- Mice
- Mycobacterium smegmatis -- drug effects
- Mycobacterium tuberculosis -- drug effects
- Phenotype
- Protective Agents -- pharmacology
- Recombinant Fusion Proteins -- pharmacology
- Recombination, Genetic -- drug effects
- Spleen -- drug effects
- Th1 Cells -- drug effects
- Treatment Outcome
- Tuberculosis -- blood
- Tuberculosis Vaccines -- administration & dosage
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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