5-azacitidine in aggressive myelodysplastic syndromes regulates chromatin structure at PU.1 gene and cell differentiation capacity. [electronic resource]
Producer: 20121119Description: 1804-11 p. digitalISSN:- 1476-5551
- Aged
- Aged, 80 and over
- Antimetabolites, Antineoplastic -- pharmacology
- Azacitidine -- pharmacology
- Cell Differentiation -- drug effects
- Cell Line, Tumor
- Chromatin -- genetics
- Colony-Stimulating Factors -- pharmacology
- DNA Methylation -- drug effects
- Female
- Gene Expression Regulation, Leukemic -- drug effects
- Humans
- Male
- Middle Aged
- Myelodysplastic Syndromes -- drug therapy
- Neoplastic Stem Cells -- cytology
- Proto-Oncogene Proteins -- genetics
- Regulatory Sequences, Nucleic Acid -- drug effects
- Trans-Activators -- genetics
- Transcriptional Activation -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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