Insights into ALK-driven cancers revealed through development of novel ALK tyrosine kinase inhibitors. [electronic resource]
Producer: 20111020Description: 4920-31 p. digitalISSN:- 1538-7445
- Anaplastic Lymphoma Kinase
- Animals
- Brain -- metabolism
- Cell Line, Tumor
- Drug Synergism
- Female
- Humans
- Isoenzymes
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Nude
- Models, Molecular
- Neoplasms -- drug therapy
- Point Mutation
- Protein Kinase Inhibitors -- chemistry
- Pyridazines -- chemistry
- Receptor Protein-Tyrosine Kinases -- antagonists & inhibitors
- Sirolimus -- pharmacology
- TOR Serine-Threonine Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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