The oncogenic role of NS5A of hepatitis C virus is mediated by up-regulation of survivin gene expression in the hepatocellular cell through p53 and NF-κB pathways. [electronic resource]
Producer: 20120606Description: 1225-32 p. digitalISSN:- 1095-8355
- Apoptosis
- Carcinoma, Hepatocellular -- genetics
- Down-Regulation
- Gene Expression
- Hep G2 Cells
- Hepacivirus -- physiology
- Humans
- Immunohistochemistry
- Inhibitor of Apoptosis Proteins -- genetics
- Liver Neoplasms -- genetics
- NF-kappa B -- metabolism
- Nitric Oxide Synthase Type II -- genetics
- Oncogenes -- physiology
- Signal Transduction
- Transfection
- Tumor Suppressor Protein p53 -- genetics
- Up-Regulation
- Viral Nonstructural Proteins -- metabolism
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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