The oncogenic role of NS5A of hepatitis C virus is mediated by up-regulation of survivin gene expression in the hepatocellular cell through p53 and NF-κB pathways.

Jiang, Yong-Fang

The oncogenic role of NS5A of hepatitis C virus is mediated by up-regulation of survivin gene expression in the hepatocellular cell through p53 and NF-κB pathways. [electronic resource] - Cell biology international Dec 2011 - 1225-32 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1095-8355

10.1042/CBI20110102 doi


Apoptosis
Carcinoma, Hepatocellular--genetics
Down-Regulation
Gene Expression
Hep G2 Cells
Hepacivirus--physiology
Humans
Immunohistochemistry
Inhibitor of Apoptosis Proteins--genetics
Liver Neoplasms--genetics
NF-kappa B--metabolism
Nitric Oxide Synthase Type II--genetics
Oncogenes--physiology
Signal Transduction
Transfection
Tumor Suppressor Protein p53--genetics
Up-Regulation
Viral Nonstructural Proteins--metabolism