The helminth product ES-62 protects against septic shock via Toll-like receptor 4-dependent autophagosomal degradation of the adaptor MyD88. [electronic resource]
Producer: 20110606Description: 344-51 p. digitalISSN:- 1529-2916
- Animals
- Autophagy -- drug effects
- Cells, Cultured
- Female
- Helminth Proteins -- pharmacology
- Humans
- Immunoblotting
- Inflammation Mediators -- immunology
- Macrophages -- drug effects
- Male
- Mice
- Mice, Inbred C57BL
- Mice, Knockout
- Microscopy, Confocal
- Microscopy, Electron
- Myeloid Differentiation Factor 88 -- immunology
- Phagosomes -- drug effects
- Shock, Septic -- genetics
- Signal Transduction -- drug effects
- Toll-Like Receptor 2 -- immunology
- Toll-Like Receptor 4 -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Retracted Publication
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