Next-generation Akt inhibitors provide greater specificity: effects on glucose metabolism in adipocytes. [electronic resource]
Producer: 20110916Description: 539-44 p. digitalISSN:- 1470-8728
- 3T3-L1 Cells
- Adipocytes -- drug effects
- Animals
- Antineoplastic Agents -- pharmacology
- Cells, Cultured
- Dose-Response Relationship, Drug
- Drug Evaluation, Preclinical
- Glucose -- metabolism
- Glucose Transporter Type 4 -- metabolism
- Heterocyclic Compounds, 3-Ring -- pharmacology
- Humans
- Mice
- Protein Kinase Inhibitors -- pharmacology
- Protein Transport -- drug effects
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- Substrate Specificity -- drug effects
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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