Next-generation Akt inhibitors provide greater specificity: effects on glucose metabolism in adipocytes.

Tan, Shixiong

Next-generation Akt inhibitors provide greater specificity: effects on glucose metabolism in adipocytes. [electronic resource] - The Biochemical journal Apr 2011 - 539-44 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1470-8728

10.1042/BJ20110040 doi


3T3-L1 Cells
Adipocytes--drug effects
Animals
Antineoplastic Agents--pharmacology
Cells, Cultured
Dose-Response Relationship, Drug
Drug Evaluation, Preclinical
Glucose--metabolism
Glucose Transporter Type 4--metabolism
Heterocyclic Compounds, 3-Ring--pharmacology
Humans
Mice
Protein Kinase Inhibitors--pharmacology
Protein Transport--drug effects
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
Substrate Specificity--drug effects