Persistence of psychosine in brain lipid rafts is a limiting factor in the therapeutic recovery of a mouse model for Krabbe disease. [electronic resource]
Producer: 20110503Description: 352-64 p. digitalISSN:- 1097-4547
- Animals
- Animals, Newborn
- Bone Marrow Transplantation -- methods
- Brain -- pathology
- Cells, Cultured
- Cholera Toxin -- metabolism
- Clathrin
- Disease Models, Animal
- Endocytosis -- genetics
- Enzyme Replacement Therapy -- methods
- Galactosylceramidase -- genetics
- Humans
- Leukodystrophy, Globoid Cell -- pathology
- Mass Spectrometry
- Membrane Microdomains -- drug effects
- Mice
- Neurons -- pathology
- Protein Kinase C -- metabolism
- Psychosine -- metabolism
- Time Factors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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