Persistence of psychosine in brain lipid rafts is a limiting factor in the therapeutic recovery of a mouse model for Krabbe disease.

White, A B

Persistence of psychosine in brain lipid rafts is a limiting factor in the therapeutic recovery of a mouse model for Krabbe disease. [electronic resource] - Journal of neuroscience research Mar 2011 - 352-64 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

1097-4547

10.1002/jnr.22564 doi


Animals
Animals, Newborn
Bone Marrow Transplantation--methods
Brain--pathology
Cells, Cultured
Cholera Toxin--metabolism
Clathrin
Disease Models, Animal
Endocytosis--genetics
Enzyme Replacement Therapy--methods
Galactosylceramidase--genetics
Humans
Leukodystrophy, Globoid Cell--pathology
Mass Spectrometry
Membrane Microdomains--drug effects
Mice
Neurons--pathology
Protein Kinase C--metabolism
Psychosine--metabolism
Time Factors