Separation of post-translational modifications in monoclonal antibodies by exploiting subtle conformational changes under mildly acidic conditions. [electronic resource]
Producer: 20101230Description: 6496-502 p. digitalISSN:- 1873-3778
- Antibodies, Monoclonal -- chemistry
- Calorimetry, Differential Scanning
- Chromatography, High Pressure Liquid -- methods
- Chromatography, Ion Exchange -- methods
- Circular Dichroism
- Glycosylation
- Humans
- Hydrogen-Ion Concentration
- Methionine -- chemistry
- Models, Molecular
- Oxidation-Reduction
- Peptide Mapping
- Protein Conformation
- Protein Denaturation
- Protein Processing, Post-Translational
- Spectrophotometry, Ultraviolet
- Temperature
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Publication Type: Journal Article
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