Induction of in vivo synthetic lethal RNAi responses to treat glioblastoma. [electronic resource]
Producer: 20100520Description: 2306-13 p. digitalISSN:- 1555-8576
- Animals
- Apoptosis
- Brain Neoplasms -- genetics
- ErbB Receptors -- antagonists & inhibitors
- Genes, Lethal -- genetics
- Glioblastoma -- genetics
- Humans
- Immunoblotting
- In Situ Nick-End Labeling
- Longevity
- Mice
- Mice, Nude
- Protein Structure, Tertiary -- genetics
- Proto-Oncogene Proteins c-akt -- antagonists & inhibitors
- RNA, Double-Stranded -- genetics
- RNA, Small Interfering -- administration & dosage
- Survival Rate
- Tumor Cells, Cultured
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
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