Induction of in vivo synthetic lethal RNAi responses to treat glioblastoma.
Michiue, Hiroyuki
Induction of in vivo synthetic lethal RNAi responses to treat glioblastoma. [electronic resource] - Cancer biology & therapy Dec 2009 - 2306-13 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
1555-8576
10.4161/cbt.8.23.10271 doi
Animals
Apoptosis
Brain Neoplasms--genetics
ErbB Receptors--antagonists & inhibitors
Genes, Lethal--genetics
Glioblastoma--genetics
Humans
Immunoblotting
In Situ Nick-End Labeling
Longevity
Mice
Mice, Nude
Protein Structure, Tertiary--genetics
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
RNA, Double-Stranded--genetics
RNA, Small Interfering--administration & dosage
Survival Rate
Tumor Cells, Cultured
Xenograft Model Antitumor Assays
Induction of in vivo synthetic lethal RNAi responses to treat glioblastoma. [electronic resource] - Cancer biology & therapy Dec 2009 - 2306-13 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
1555-8576
10.4161/cbt.8.23.10271 doi
Animals
Apoptosis
Brain Neoplasms--genetics
ErbB Receptors--antagonists & inhibitors
Genes, Lethal--genetics
Glioblastoma--genetics
Humans
Immunoblotting
In Situ Nick-End Labeling
Longevity
Mice
Mice, Nude
Protein Structure, Tertiary--genetics
Proto-Oncogene Proteins c-akt--antagonists & inhibitors
RNA, Double-Stranded--genetics
RNA, Small Interfering--administration & dosage
Survival Rate
Tumor Cells, Cultured
Xenograft Model Antitumor Assays