Regulation of heme synthesis and proteasomal activity by copper: possible implications for Wilson's disease. [electronic resource]
Producer: 20091117Description: 209-21 p. digitalISSN:- 2162-6537
- Adenosine Triphosphatases -- biosynthesis
- Carcinoma, Hepatocellular -- drug therapy
- Cation Transport Proteins -- biosynthesis
- Cell Line, Tumor
- Cell Survival -- drug effects
- Copper -- toxicity
- Copper-Transporting ATPases
- Disulfiram -- pharmacology
- Down-Regulation -- drug effects
- Enzyme Inhibitors -- toxicity
- Heme -- biosynthesis
- Hepatocytes -- drug effects
- Hepatolenticular Degeneration
- Humans
- Hydroxymethylbilane Synthase -- antagonists & inhibitors
- Liver Neoplasms -- drug therapy
- Porphobilinogen Synthase -- antagonists & inhibitors
- Proteasome Endopeptidase Complex -- drug effects
- Protoporphyrins -- metabolism
- Reactive Oxygen Species -- metabolism
- Ubiquitin -- metabolism
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Publication Type: Journal Article
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