MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development. [electronic resource]
Producer: 20091027Description: 856-66 p. digitalISSN:- 1525-2191
- Animals
- Cell Proliferation
- Cell Transformation, Neoplastic -- metabolism
- Ganglia, Sympathetic
- Homeodomain Proteins -- analysis
- Humans
- Mice
- Mice, Transgenic
- N-Myc Proto-Oncogene Protein
- Neoplastic Stem Cells -- metabolism
- Neuroblastoma -- metabolism
- Neurons -- metabolism
- Nuclear Proteins -- genetics
- Oncogene Proteins -- genetics
- Promoter Regions, Genetic
- Rats
- Transcription Factors -- analysis
- Tyrosine 3-Monooxygenase -- genetics
- Xenograft Model Antitumor Assays
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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