MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development.

Alam, Goleeta

MYCN promotes the expansion of Phox2B-positive neuronal progenitors to drive neuroblastoma development. [electronic resource] - The American journal of pathology Aug 2009 - 856-66 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1525-2191

10.2353/ajpath.2009.090019 doi


Animals
Cell Proliferation
Cell Transformation, Neoplastic--metabolism
Ganglia, Sympathetic
Homeodomain Proteins--analysis
Humans
Mice
Mice, Transgenic
N-Myc Proto-Oncogene Protein
Neoplastic Stem Cells--metabolism
Neuroblastoma--metabolism
Neurons--metabolism
Nuclear Proteins--genetics
Oncogene Proteins--genetics
Promoter Regions, Genetic
Rats
Transcription Factors--analysis
Tyrosine 3-Monooxygenase--genetics
Xenograft Model Antitumor Assays