Chemical genomics identifies the unfolded protein response as a target for selective cancer cell killing during glucose deprivation. [electronic resource]
Producer: 20090708Description: 4225-34 p. digitalISSN:- 1538-7445
- Activating Transcription Factor 4 -- drug effects
- Cell Death
- Cell Survival -- drug effects
- DNA-Binding Proteins -- drug effects
- Gene Expression Profiling
- Genes, Reporter
- Genomics
- Glucose -- deficiency
- Humans
- Hypoglycemic Agents -- pharmacology
- Macrolides -- pharmacology
- Neoplasms -- drug therapy
- Oligosaccharides -- pharmacology
- Phenformin -- pharmacology
- Plasmids
- Protein Denaturation -- genetics
- Protein Folding -- drug effects
- Regulatory Factor X Transcription Factors
- Transcription Factors -- drug effects
- Transfection
- X-Box Binding Protein 1
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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