Chemical genomics identifies the unfolded protein response as a target for selective cancer cell killing during glucose deprivation.
Saito, Sakae
Chemical genomics identifies the unfolded protein response as a target for selective cancer cell killing during glucose deprivation. [electronic resource] - Cancer research May 2009 - 4225-34 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1538-7445
10.1158/0008-5472.CAN-08-2689 doi
Activating Transcription Factor 4--drug effects
Cell Death
Cell Survival--drug effects
DNA-Binding Proteins--drug effects
Gene Expression Profiling
Genes, Reporter
Genomics
Glucose--deficiency
Humans
Hypoglycemic Agents--pharmacology
Macrolides--pharmacology
Neoplasms--drug therapy
Oligosaccharides--pharmacology
Phenformin--pharmacology
Plasmids
Protein Denaturation--genetics
Protein Folding--drug effects
Regulatory Factor X Transcription Factors
Transcription Factors--drug effects
Transfection
X-Box Binding Protein 1
Chemical genomics identifies the unfolded protein response as a target for selective cancer cell killing during glucose deprivation. [electronic resource] - Cancer research May 2009 - 4225-34 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1538-7445
10.1158/0008-5472.CAN-08-2689 doi
Activating Transcription Factor 4--drug effects
Cell Death
Cell Survival--drug effects
DNA-Binding Proteins--drug effects
Gene Expression Profiling
Genes, Reporter
Genomics
Glucose--deficiency
Humans
Hypoglycemic Agents--pharmacology
Macrolides--pharmacology
Neoplasms--drug therapy
Oligosaccharides--pharmacology
Phenformin--pharmacology
Plasmids
Protein Denaturation--genetics
Protein Folding--drug effects
Regulatory Factor X Transcription Factors
Transcription Factors--drug effects
Transfection
X-Box Binding Protein 1