Mutations of P450c21 (steroid 21-hydroxylase) at Cys428, Val281, and Ser268 result in complete, partial, or no loss of enzymatic activity, respectively. [electronic resource]
Producer: 19910910Description: 519-23 p. digitalISSN:- 0021-9738
- Adrenal Hyperplasia, Congenital -- enzymology
- Amino Acid Sequence
- Animals
- Base Sequence
- Cell Line
- Heme -- metabolism
- Humans
- Kinetics
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Oligonucleotides
- Sequence Alignment
- Steroid 21-Hydroxylase -- chemistry
- Structure-Activity Relationship
- Transfection
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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