A chemical compound commonly used to inhibit PKR, {8-(imidazol-4-ylmethylene)-6H-azolidino[5,4-g] benzothiazol-7-one}, protects neurons by inhibiting cyclin-dependent kinase. [electronic resource]
Producer: 20090309Description: 2003-16 p. digitalISSN:- 1460-9568
- Animals
- Animals, Newborn
- Apoptosis -- drug effects
- Benzothiazoles -- pharmacology
- Cell Cycle -- drug effects
- Cell Line
- Cyclin-Dependent Kinases -- antagonists & inhibitors
- Enzyme Inhibitors -- pharmacology
- Eukaryotic Initiation Factor-2 -- drug effects
- Humans
- Imidazoles -- pharmacology
- Nerve Degeneration -- drug therapy
- Neurodegenerative Diseases -- drug therapy
- Neurons -- drug effects
- Rats
- Rats, Wistar
- eIF-2 Kinase -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, N.I.H., Extramural
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