Oncocalyxone A inhibits human platelet aggregation by increasing cGMP and by binding to GP Ibalpha glycoprotein. [electronic resource]
Producer: 20081125Description: 1216-24 p. digitalISSN:- 0007-1188
- Adenosine Diphosphate -- pharmacology
- Adenosine Triphosphate -- metabolism
- Adolescent
- Adult
- Anthraquinones -- isolation & purification
- Blood Platelets -- drug effects
- Cyclic AMP -- biosynthesis
- Cyclic GMP -- blood
- Cyclic Nucleotide Phosphodiesterases, Type 5 -- blood
- Female
- Flow Cytometry
- Guanylate Cyclase -- blood
- Humans
- In Vitro Techniques
- Male
- Middle Aged
- Nitric Oxide -- metabolism
- Platelet Aggregation -- drug effects
- Platelet Aggregation Inhibitors -- metabolism
- Platelet Glycoprotein GPIb-IX Complex -- metabolism
- Protein Binding
- Thromboxane A2 -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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