Oxygen dependence and extravascular transport of hypoxia-activated prodrugs: comparison of the dinitrobenzamide mustard PR-104A and tirapazamine. [electronic resource]
Producer: 20071109Description: 560-71 p. digitalISSN:- 0360-3016
- Animals
- Antineoplastic Agents -- pharmacokinetics
- Biological Transport
- Cell Hypoxia -- physiology
- Drug Evaluation, Preclinical
- Humans
- Mice
- Mice, Nude
- Models, Biological
- Nitrogen Mustard Compounds -- pharmacokinetics
- Oxygen -- physiology
- Partial Pressure
- Prodrugs -- pharmacokinetics
- Radiation-Sensitizing Agents -- pharmacokinetics
- Tirapazamine
- Triazines -- pharmacokinetics
- Tumor Cells, Cultured
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Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
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