An oral adsorbent, AST-120 protects against the progression of oxidative stress by reducing the accumulation of indoxyl sulfate in the systemic circulation in renal failure. [electronic resource]
Producer: 20070720Description: 1283-9 p. digitalISSN:- 0724-8741
- Administration, Oral
- Animals
- Antioxidants -- administration & dosage
- Biomarkers -- blood
- Carbon -- administration & dosage
- Cells, Cultured
- Disease Models, Animal
- Dose-Response Relationship, Drug
- Endothelial Cells -- drug effects
- Gene Expression -- drug effects
- Humans
- Indican -- blood
- Kidney Failure, Chronic -- drug therapy
- Male
- Nephrectomy
- Organic Anion Transport Protein 1 -- genetics
- Oxidation-Reduction
- Oxidative Stress -- drug effects
- Oxides -- administration & dosage
- RNA, Messenger -- metabolism
- Rats
- Rats, Wistar
- Reactive Oxygen Species -- metabolism
- Serum Albumin -- metabolism
- Time Factors
- Transforming Growth Factor beta1 -- genetics
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Publication Type: Journal Article
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