TIMP-1 promotes age-related renal fibrosis through upregulating ICAM-1 in human TIMP-1 transgenic mice. [electronic resource]
Producer: 20070305Description: 1130-43 p. digitalISSN:- 1079-5006
- Aging -- physiology
- Albuminuria
- Animals
- Collagen Type III -- genetics
- Collagen Type IV -- genetics
- Creatinine -- blood
- Down-Regulation -- physiology
- Fibrosis
- Gene Expression
- Genotype
- Humans
- Intercellular Adhesion Molecule-1 -- genetics
- Kidney -- pathology
- Macrophages -- metabolism
- Matrix Metalloproteinase 2 -- genetics
- Matrix Metalloproteinase 9 -- genetics
- Mice
- Mice, Transgenic
- Models, Animal
- RNA, Messenger -- metabolism
- Tissue Inhibitor of Metalloproteinase-1 -- genetics
- Tissue Inhibitor of Metalloproteinase-2 -- genetics
- Transforming Growth Factor beta1 -- genetics
- Up-Regulation -- physiology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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