Induction of G2/M phase arrest and apoptosis of human leukemia cells by potent antitumor triazoloacridinone C-1305. [electronic resource]
Producer: 20070130Description: 1668-79 p. digitalISSN:- 0006-2952
- Acridines -- chemistry
- Adenosine Triphosphate -- metabolism
- Antineoplastic Agents -- chemistry
- Apoptosis -- drug effects
- Blotting, Western
- Caspase 3 -- metabolism
- Cell Division -- drug effects
- Cell Line, Tumor
- Cell Proliferation -- drug effects
- Electrophoresis, Agar Gel
- Flow Cytometry
- G2 Phase -- drug effects
- HL-60 Cells
- Humans
- In Situ Nick-End Labeling
- Intracellular Membranes -- drug effects
- Leukemia
- Membrane Potentials -- drug effects
- Mitochondria -- drug effects
- Poly (ADP-Ribose) Polymerase-1
- Poly(ADP-ribose) Polymerases -- metabolism
- Triazoles -- chemistry
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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