Emodin inhibits TNF alpha-induced MMP-1 expression through suppression of activator protein-1 (AP-1). [electronic resource]
Producer: 20070129Description: 2480-5 p. digitalISSN:- 0024-3205
- Anthracenes -- pharmacology
- Blotting, Western
- Cells, Cultured
- Dose-Response Relationship, Drug
- Emodin -- pharmacology
- Fibroblasts -- cytology
- Flavonoids -- pharmacology
- Humans
- Imidazoles -- pharmacology
- Infant, Newborn
- JNK Mitogen-Activated Protein Kinases -- antagonists & inhibitors
- Luciferases -- genetics
- Male
- Matrix Metalloproteinase 1 -- biosynthesis
- Mitogen-Activated Protein Kinase 1 -- antagonists & inhibitors
- Mitogen-Activated Protein Kinase 3 -- antagonists & inhibitors
- Phosphorylation -- drug effects
- Promoter Regions, Genetic -- genetics
- Pyridines -- pharmacology
- Rheum -- chemistry
- Transcription Factor AP-1 -- antagonists & inhibitors
- Transfection
- Tumor Necrosis Factor-alpha -- pharmacology
- p38 Mitogen-Activated Protein Kinases -- antagonists & inhibitors
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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