HMG-CoA reductase inhibitors inhibit rat propylthiouracil-induced goiter by modulating the ras-MAPK pathway. [electronic resource]
Producer: 20070427Description: 967-73 p. digitalISSN:- 0946-2716
- Animals
- Disease Models, Animal
- Extracellular Signal-Regulated MAP Kinases -- metabolism
- Flavonoids -- pharmacology
- Gene Transfer Techniques
- Goiter -- chemically induced
- Hydroxymethylglutaryl-CoA Reductase Inhibitors -- pharmacology
- Hyperplasia
- Hypertrophy
- Lovastatin -- pharmacology
- MAP Kinase Signaling System -- drug effects
- Male
- Phosphorylation
- Proliferating Cell Nuclear Antigen -- analysis
- Propylthiouracil
- Protein Kinase Inhibitors -- pharmacology
- Protein Prenylation -- drug effects
- Rats
- Rats, Wistar
- Terpenes -- metabolism
- Thyroid Gland -- drug effects
- Thyrotropin -- blood
- ras Proteins -- genetics
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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