ABCB1 modulation does not circumvent drug extrusion from primitive leukemic progenitor cells and may preferentially target residual normal cells in acute myelogenous leukemia. [electronic resource]
Producer: 20071109Description: 3452-8 p. digitalISSN:- 1078-0432
- ADP-ribosyl Cyclase 1 -- analysis
- ATP Binding Cassette Transporter, Subfamily B
- ATP Binding Cassette Transporter, Subfamily B, Member 1 -- drug effects
- Adolescent
- Adult
- Aged
- Antigens, CD34 -- biosynthesis
- Antigens, Differentiation -- biosynthesis
- Biological Transport -- drug effects
- Bone Marrow Cells -- drug effects
- Cyclosporins -- pharmacology
- Drug Resistance, Multiple
- Female
- Flow Cytometry
- Hematopoietic Stem Cells -- drug effects
- Humans
- Leukemia, Myeloid, Acute -- drug therapy
- Male
- Middle Aged
- Mitoxantrone -- antagonists & inhibitors
- Oncogene Proteins, Fusion -- biosynthesis
- Reverse Transcriptase Polymerase Chain Reaction -- methods
- Verapamil -- pharmacology
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Publication Type: Journal Article; Research Support, Non-U.S. Gov't
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